RRP Awareness Day: June 11

Hope on the horizon

RRP Awareness Day is an international event to raise awareness about recurrent respiratory papillomatosis (RRP), a debilitating disease driven by chronic HPV 6/11 viral infection.

With new research and innovations, we believe that hope is on the horizon for the RRP community.

On June 11th at the 2025 International RRP Awareness Day, we heard from from RRP patients, their caregivers, and the healthcare community supporting them about:

Patient and caregiver experience with RRP
Significant burden of living with RRP
Challenges of repeated surgeries and risk of irreversible injury
Need for new innovations

CO-HOSTS

RRP FOUNDATION

Kim McClellan, President

PRECIGEN

Helen Sabzevari, PhD, President and CEO

ATTENDEES

RRP patients
Caregivers and family members
Healthcare providers
Community supporting RRP patients

Scenes from RRP Awareness Day 2025

~27K

Estimated adult RRP Patients in the United States¹

125K+

Estimated RRP patients outside the United States¹

Juvenile Onset RRP

Adult
Onset RRP

The vast majority of burden is on the adult population, with ~95% of unique patients over the age of 18

About RRP

RRP is a serious and debilitating disease driven by chronic HPV 6/11 viral infection. RRP impacts both children and adults and is characterized by papilloma growths in the respiratory tract that can result in severe voice disturbance, compromised airway, and recurrent post-obstructive pneumonias. Although rare, RRP has the potential for transformation to malignant cancer and can be fatal.²

Repeated surgeries do not address underlying cause of RRP

RRP is a chronic disease caused by HPV 6/11 and repeated surgeries to treat symptoms do not address the underlying cause of the disease.

RRP patients experience significant lifetime burden

RRP patients experience significant burden of disease with ongoing risks associated with repeated surgeries, emotional distress, and crippling economic burden to families and the healthcare system overall. 

Repeated surgeries carry high risk for irreversible damage

Recurrence of papilloma after surgical removal is very common and patients frequently require dozens to hundreds of lifetime surgeries. Risk of significant irreversible injury rises with each surgical intervention.³

Spread the Word

One powerful way to support RRP Awareness is by sharing information online. Join us to spread awareness about this devastating disease.

Patient Stories

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Mike's StoryHear how RRP impacted this devoted husband, caring father, and respected member of his community