RRP Awareness Day: June 11, 2025

Hope on the horizon

RRP Awareness Day is an international event to raise awareness about recurrent respiratory papillomatosis (RRP), a debilitating disease driven by chronic HPV 6/11 viral infection.

With new research and innovations, we believe that hope is on the horizon for the RRP community.

Join the RRP Awareness Day global webcast on June 11th to hear from RRP patients, their caregivers, and the healthcare community supporting them about:

  • Patient and caregiver experience with RRP
  • Significant burden of living with RRP
  • Challenges of repeated surgeries and risk of irreversible injury
  • Need for new innovations

CO-HOSTS

RRP FOUNDATION

Kim McClellan, President

PRECIGEN

Helen Sabzevari, PhD, President and CEO

WHO SHOULD ATTEND

  • RRP patients
  • Caregivers and family members
  • Healthcare providers
  • Community supporting RRP patients

~27K

Estimated adult RRP Patients in the United States1

125K+

Estimated RRP patients outside the United States1

Juvenile Onset RRP

More aggressive disease has been linked to earlier age of onset

Adult
Onset RRP

The vast majority of burden is on the adult population, with ~95% of unique patients over the age of 18

About RRP

RRP is a serious and debilitating disease driven by chronic HPV 6/11 viral infection. RRP impacts both children and adults and is characterized by papilloma growths in the respiratory tract that can result in severe voice disturbance, compromised airway, and recurrent post-obstructive pneumonias. Although rare, RRP has the potential for transformation to malignant cancer and can be fatal.2

Repeated surgeries do not address underlying cause of RRP

There is no cure for RRP and no FDA-approved therapy.  The current standard-of-care is repeated surgeries to treat symptoms, which do not address the underlying cause of the disease.

RRP patients experience significant lifetime burden

RRP patients experience significant burden of disease with ongoing risks associated with repeated surgeries, emotional distress, and crippling economic burden to families and the healthcare system overall.


Repeated surgeries carry high risk for irreversible damage

Recurrence of papilloma after surgical removal is very common and patients frequently require dozens to hundreds of lifetime surgeries. Risk of significant irreversible injury rises with each surgical intervention.3

Spread the Word

One powerful way to support RRP Awareness is by sharing information online. Join us to spread awareness about this devastating disease.

1Precigen internal research of claims data and electronic health records 2024-2025
2Norberg et al., Lancet Respir. Med 2025; Online First
3So et al., Otolaryngol Head Neck Surg 2024; 170(4): 1091-1098